Sr. Scientist

The primary responsibility is to provide anatomic pathology leadership to oncology drug discovery and development programs at Millennium, typically involving novel therapeutic molecular targets. This includes stewardship of pathology/toxicology studies and subsequent support of regulatory affairs and clinical development efforts. The incumbent will also be responsible for providing guidance to R&D scientific staff as well as Millennium senior management on matters pertaining to pathology/toxicology, and serving as a Drug Safety Evaluation representative on drug discovery and development project teams for small organic molecules and antibody drug conjugates.DUTIES & RESPONSIBILITIES- We currently have an opening for an Anatomic Pathologist to perform the complex microscopic evaluation and interpretation of tissue sections from animals exposed to test materials and correlate these findings with necropsy, organ weight and clinical pathology findings.
- This position authors comprehensive pathology narrative reports of microscopic, gross, and clinical pathology findings, while meeting report deadlines, and supervises necropsies and provide scientific guidance to necropsy technicians to ensure accuracy and compliance with protocols and SOP.
- Contribute to regulatory submission as required and represent the company at regulatory meetings
- Collaborate in the development and presentation of strategies for managing pathology/toxicology-related issues
- Interface with project leaders in various Takeda locations (ie. Cambridge, Shonan, San Diego and San Francisco) to ensure a seamless transition of discovery programs to development
- Represent Millennium in external scientific venues, e.g., Society of Toxicology, American College of Veterinary Pathology, Society of Toxicologic PathologyQUALIFICATIONS- DVM and PhD; with board certification in anatomic pathology (ACVP), preferably with 1-2 years of related experience are essential.
- Must have strong background in molecular biology;
- Preferred skills include:
background in , pharmacology, toxicology and/or biochemistry.
- Familiar with the application of in vitro or animal models in determining the biological consequence of modulation of a molecular target
- Experience in designing, conducting, and reporting studies with an understanding of the strategic applications of findings.
- Experienced with Microsoft Office applications.