The Associate Director/Director, Health Economics and Outcomes Research (HEOR) role sits within the Evidence Generation function of the United States (US) Medical Affairs (USMA) organization and interacts with Payer and Commercial teams to design and implement observational research strategies in support of AZ products. Activities focus on the generation of evidence to assist payer and health care provider (HCP) decision-makers and include scientific evidence for reimbursement dossiers and market access in the US. This role supports the internal and external communication of the clinical and economic value proposition and of scientific results to achieve maximal scientific impact and commercial success of AZ products throughout their life cycle. This position requires an individual with expert scientific knowledge of HEOR and its application throughout development process, strong business acumen, and excellent interpersonal skills. br br Accountabilities: br br * Lead (Director)/Support (Assoc. Director) the development and execution of the evidence generation strategy to support articulation of product clinical and economic value. br * Lead (Director)/Support (Assoc. Director) US input to brand strategy and Medical Plan, payer-related evidence plan, and market access & pricing strategy. br * Proactively and independently, contribute to research planning process and resolution of complex issues, especially if they affect market access decisions and evidence for product. br * Represent HEOR as member of the Core Medical Team (CMT). br * Co-Lead (Director) the Clinical Value Team (CVT) with USMA Managed Markets. br * Lead (Director)/Support (Assoc. Director) CMT/CVT members to develop strategy and execute a response to value reviews of AZ products by external organizations, as appropriate and in alignment with current AZ approach. br * Ensure US evidence strategy alignment with Global Medical Affairs, reimbursement, and regulatory strategies. br * Serve as observational research expert within Therapeutic Area (TA). br * Remain actively aware of the product environment by establishing, maintaining, and fostering internal (cross-functional, within the US and Global organizations) and external interactions with scientific experts. br br Responsibilities: br * Design, protocol development, championing through governance, execution, and communication of observational research and pharmacoeconomic analyses (e.g., retrospective database analyses, payer analytic tools, systematic reviews, network meta-analyses, budget impact models, cost effectiveness models). br * Collaboration with Field Medical Affairs teams to compile evidence required to satisfy payer requirements, as necessary. br * Integration of the US payer viewpoint into Global development and reimbursement strategies. br * Identification and effective use of internal and external data sources and/or research to support payer reimbursement dossiers and payer value propositions. br * Input for the preparation of reimbursement/formulary documents. br * Maintain current and in-depth understanding of HEOR analytical methodologies.