Associate Scientist/Scientist, Cell Line Development
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POST DATE 9/18/2016
END DATE 10/15/2016
OncoMed Pharmaceuticals, Inc.
Redwood City, CA
JOB DESCRIPTIONAPPLY Job Summary
The cell line development group at OncoMed is looking for a creative, highly motivated individual with expertise in molecular and cell biology. The Associate Scientist/Scientist will be a critical member of the group which focuses on the generation of highly productive CHO cell lines with desired protein quality attributes for the production of oncology biotherapeutics. The candidate effectively plans and executes experiments, and clearly communicates results.
Perform CHO cell line development to generate manufacturing cell lines secreting novel therapeutic proteins. This work includes transfection, selection, single cell cloning with imaging, cell banking, and evaluation of clonal cell lines for productivity, quality, and stability
Utilize imaging equipment for confirming monoclonality and microbioreactors for fed batch evaluations
Work with CMO s to transfer banking and inoculum expansion processes
Stay up to date on published literature and develop innovative cell line development technologies
Maintain clearly written and well-organized lab notebooks, write technical reports, and contribute to regulatory filings
Analyze and present results in meetings
Interact with cell culture and purification process development, analytical, research groups, and partner companies