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Senior Director, Bioinformatics and Data Science

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POST DATE 9/13/2016
END DATE 6/8/2017

Dana-Farber Cancer Institute Boston, MA

Boston, MA
AJE Ref #
Job Classification
Full Time
Job Type
Company Ref #
Mid-Career (2 - 15 years)



Within the office of the Chief Health Information Officer, the Director of Bioinformatics will serve Dana-Farber Cancer Institute and its patients by building and leading a small, central team of bioinformaticists and computational biologists, developing methods, analysis tools, and pipelines as needed to support Clinical and Research communities, and by helping coordinate, harmonize, and ensure the excellence of bioinformatics-related support activities across the Institute. The role requires a strong background in bioinformatics and genomics and their applications in biomedical research and oncology clinical care, as well as a high level of communication, interpersonal, and team-building skills.



* Manage a small, versatile team of bioinformaticists, computational biologists, and other informatics professionals to tackle high-priority and cross-functional DFCI institutional needs

* Collaborate with research information services, scientific computing, data science and engineering teams to create and manage multidisciplinary project teams.

* Collaborate with strategic Centers and functions, such as the Knowledge Systems group to design and build translational/genomic research systems and decision-support models that integrate research and clinical data, and support precision cancer medicine efforts.

* Help develop a standardized data management, access, integration, and analysis strategy and approach for translational / 'omic data for Dana-Farber and our strategic partner institutions.

* Support and participate in methods development and data analysis strategy for the PROFILE precision medicine program, CCGD (Center for Cancer Genome Discovery), Center for Cancer Precision Medicine (CCPM), and other strategic centers at Dana-Farber.

* Support PROFILE/CCGD project bioinformatics research and development: Provide expertise and foster collaborative decision-making and research efforts around new methods, tools, and data. Collaborative work may include integration of somatic and Germline DNA, copy number, RNAseq, immune profiling, etc. to support both clinical decision-making and research needs. Help maintain DFCI's leading position in cancer molecular profiling and use of genomic data in clinical practice. Provide scientific informatics mentorship to PROFILE/CCGD bioinformatics team.

* Collaborate with Pathology leadership and informatics personnel from BW and DFCI to continue advancing and help systematize scientific, pipeline, and process improvements, including support for scientific and clinical interpretation of genomic assay results.

* Collaborate with Radiation Oncology leadership and informatics personnel from BWH and DFCI to continue advancing scientific and process improvements and to support development of research databases, informatics workflow software, and analytics/reporting tools.

* Assemble appropriate governance bodies to support prioritization or work, strategic directions, and tactical decisions

* Help cultivate and support a DFCI network of bioinformaticists and computational biologists. Establish and maintain community of practice for best-practice and expertise-sharing, collaborations, mentorship, and career development for staff bioinformatics personnel of all levels across the institute

* Supply scientific expertise for internal software development projects.

* Interact with senior executives, management, and all levels of faculty and staff on current and future initiatives to ensure high-quality, high-impact decisions on technical/scientific solutions and innovative projects in the biological and translational research areas.

* Ensure all employees are treated with dignity and respect, have appropriate performance feedback and career development conversations and support, and have the tools they need to do their jobs.



* Ten years of bioinformatics and genomics-related professional experience, including at least 5 years of people management in a biomedical research setting. Industry experience preferred.

* Strong technical and scientific background with hands-on experience and proficiency.

* Doctorate in Bioinformatics or Computational Biology, or equivalent experience, including a strong scientific publication record.

* At least three years of relevant experience in the oncology domain.


* Proven leadership, strategic, and execution abilities

* Excellent verbal and written communications skills, with ability to deliver compelling, persuasive presentations to technical, scientific, and administrative audiences

* Exceptional interpersonal and collaboration skills, demonstrated ability to be effective within a complex organizational structure

* Ability to set and manage annual budget and goals, and to manage a portfolio of multiple simultaneous projects with defined deadlines, using a combination of matrix and direct resources

* Keen attention to detail

* Superior analytical, evaluative, and problem-solving abilities

* Exceptional service orientation

* Ability to motivate and inspire others in a team-oriented, collaborative environment

* Ability to work under minimal supervision in complex environments

* Ability to effectively manage client and partner expectations

* Ability to interact professionally with senior executives

* Ability to establish immediate credibility among peers -- a professional who is respected for intelligence and technical expertise