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Lab Manager - Marasco Lab (Cancer Immunology & Virology)

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POST DATE 9/17/2016
END DATE 6/3/2017

Dana-Farber Cancer Institute Boston, MA

Boston, MA
AJE Ref #
Job Classification
Full Time
Job Type
Company Ref #
Mid-Career (2 - 15 years)
Bachelors Degree



Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


A lab/database manager position within a fast-growing immunology research team is immediately available for an experienced researcher who has general laboratory management and administration skills and is also interested in scientific research.

The primary role of the Manager is to ensure a safe and efficient laboratory environment. This candidate must have laboratory management skills and take responsibility for the daily operation of the research lab, including equipment, supplies, software, and documentation. Laboratory management skills include:

* Maintaining and operating the lab s major equipment. The Laboratory Manager is to act as a technical expert/advisor on all equipment issues. This individual is responsible for training lab members on the correct use of lab equipment, evaluating and recommending new technologies, and assisting the administrative team with equipment budgets and potential equipment purchases. S/he is also responsible for planning, coordinating and directing the operations of all equipment for effective maintenance and repair programs and service contracts.

* Ordering, organizing, and restocking core lab supplies. The job requires communicating with representatives of companies marketing laboratory and scientific products and arranging for demos and/or group discounts when necessary.

* Abilities to maintain a safe, secure yet functional lab environment are a must. The manager will be responsible for organizing and allocating the space in the lab s refrigerators, freezers (-20 C, -80 C and liquid N2), and CO2 incubators as well as organizing periodical lab cleaning up. S/he will also play a central role in distributing other lab maintenance duties to technicians, fellows and/or scientists.

* Responsible for archiving bacteria glycerol stocks and plasmids, and electronically cataloging them in a computer-based laboratory database, and helping to locate archived reagents for all lab members. In addition, s/he will be responsible for creating new database archives for liquid N2 stored cells. The individual will perform reagent preparation and shipping/handling related to incoming and outgoing Material Transfer Agreements (MTAs). This includes preparation of electronic plasmid maps and QC the materials into and out of the lab

Scientifically, the individual will be responsible for creating and maintaining immunoglobulin gene databases for the research team. In this role, s/he will be responsible for analyzing immunoglobulin gene sequences that are generated in the lab and compiling amino acid sequence tables, alignments and gene family assignments for publication, including performing web based searches of gene and protein structures and functions, performing web mining, alignments, etc. As a result, the position requires a detailed understanding and working knowledge of all aspects of bioinformatics as described in the The Genome Access Course by Cold-Spring Harbor Laboratory's Genome Research Center, and the ability to apply this knowledge as support to ongoing laboratory projects.

The individual will be an integral member of the laboratory and is expected to make presentations at lab meetings. His/her intellectual input and co-authorship are encouraged.

This is a regular, full time position. Nights and weekends may be required to meet research needs.


Please include a cover letter with your application which explains your interest in this position.

* Advanced degree in biomedical sciences or related field with a MS/PhD degree in molecular biology and immunology is preferred. Bachelor's required.

* The preferred candidate will have a minimum of 3 years of experience. S/he must have previous experience managing a laboratory setting, including equipment, and be able to oversee laboratory operations immediately.

* Programming skills to manage robotics and an array of equipment is also preferred including but not limited to an automated system that consists of a Tecan liquid handler, colony picker, two power washers, two incubators and a MSD reader; a flow cytometry analyzer and a sorter; a BiaCore T100 and an OctRed 96 instrument, a multi-label plate reader and miscellaneous routine equipment.

* Proficient computer skills are also expected with competency in Word, Excel, etc with use of both PC and Mac.

* The applicant must be a self-starter with the ability to work well within a fast-growing team environment and be able to work on his/her own with minimal daily supervision.

* The individual is expected to be able to multi-task and be well organized, execute good time management skills and pay careful attention to details, as well as have excellent communication skills.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.