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POST DATE 9/17/2016
END DATE 3/22/2017

Brigham & Women's Hospital(BWH) Boston, MA

Boston, MA
AJE Ref #
Job Classification
Full Time
Job Type
Company Ref #
Entry Level (0 - 2 years)
Bachelors Degree



Working under very general supervision performs a variety of routine, but sophisticated Molecular protocols for diagnostic testing. Prepares nucleic acids from patient samples and analyzes quality and quantity. Records all procedures performed and results in laboratory notebooks and computer database. Interprets quality controls on molecular biology assays. Through literature searches and conferences with Laboratory Director, may assist in determining the most suitable methodologies to be used. May develop modifications of existing techniques under direction. May assist in the orientation and training of new laboratory staff.


1.Maintains diagnostic viability of specimens received. Prepares DNA or RNA from clinical specimens which includes handling of tissues and blood samples, centrifugation, spectrophotometry, gel electrophoresis and robotic instrumentation.

2.Under general supervision, performs a variety of routine, but sophisticated molecular protocols for diagnostic testing and determines whether results warrant repeating or modification. Protocols utilize a variety of molecular assays that are constantly evolving as the discipline develops, but includes PCR, RT-PCR, QRT-PCR, Hologic Invader Assay, capillary gel electrophoresis, Sanger sequencing, Pyrosequencing, multiplexed liquid bead microarray (Luminex), melt curve analysis (Lightscanner), Hologic Aptima HPV assay, Next Generation Sequencing and Mass Spectrometry.

3.Accurately records all procedures and results run in laboratory. Documents and follows up with senior staff any errors or failures encountered.

4.Responsible for organizing and executing entire day workload, which will vary and require adjusting to the clinical specimens obtained each day. Must work with other technologists as a team.
5.Under guidance of Laboratory Director, modifies existing protocols to improve diagnostic or experimental tests.

6.Identifies problems and brings to the attention of more senior staff. Troubleshoots problems relating to routine operations of laboratory, with supervision as required.

7.Interprets quality controls on molecular assays. Responsible for documentation of daily QA/QC charts for all laboratory equipment and assays.

8.Performs independent literature or web searches as directed.

9.May assist in orientation and training of new technologists, post-doctoral fellows and residents.

10.Prepares or handles inventory of a large number of varied reagents in the lab and maintains quality control of reagents.

11.Maintains and orders laboratory supplies as needed.

12.Maintains laboratory equipment in proper working order, following appropriate laboratory safety protocols.

13.Maintains established department policies, procedures and objectives, including the areas of quality assurance, safety, environmental and infection control.

14.Follows all JC National Patient Safety Goals and related BWH Pathology and Hospital Policies.

15.Performs all other duties and responsibilities as directed.


Minimum of a Bachelor of Science or Bachelor of Arts degree in a biological/physical science required, or other qualifications as described in the Federal Register, 42 CFR, Subpart M 493.1403 - 1495. Coursework in molecular biology and/or genetics highly desired.

0-2 years experience.


Ability to perform molecular biology techniques.

Attention to detail.

Ability and willingness to follow instructions accurately and thoroughly and to take responsibility for ones actions.

Excellent organizational skills to cope with variable and often very busy schedule and to maintain accuracy and expertise.

Exercises discretion and good judgement in dissemination of patient information.

Flexibility in coping with demands that vary from day to day.

On own initiative, ability to identify potential problems and troubleshoot problems as necessary.

Easy familiarity with basic laboratory techniques and equipment, as well as strong basic knowledge of biology, chemistry, mathematics and use of computers.

Good oral and written communication skills.

Good interpersonal skills for dealing with a wide variety of staff and clinicians.

Ability to work under general supervision.


Very busy and constantly changing laboratory environment. Can be noisy and stressful.

Exposure to solvents and chemical reagents and potential exposure to infectious agents, all under controlled conditions, minimal risk when proper procedures followed. Will be required to handle human tissue.


None. May assist in orienting and training of new technologists, post-doctoral fellows and residents.

Brigham and Womens Hospital is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, sexual orientation, protected veteran status, or on the basis of disability.

Brigham and Womens Hospital I CARE Standards

The I CARE Standards guide me in my interactions with patients, family members, visitors, colleagues, and neighbors in my workplace and surrounding community to optimize the Brigham experience and help fulfill my role in our mission of providing seamless, high quality patient and family centered care.
C.I will Communicate my commitment to high quality performance
A.I will Appear and act as a professional
R.I will Respect all individuals
E.I will Extend myself