September 21, 2016

Post Doctoral Fellow - Biomedical and Health Informatics

Children's Hospital of Philadelphia - Philadelphia, PA

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Job Description

Job Description:

A postdoctoral fellow position is open in the Bioinformatics Group at the Department of Biomedical and Health Informatics (DBHI) at the Children's Hospital of Philadelphia (CHOP), reporting to the Director of Bioinformatics.

CHOP postdoctoral fellows receive mentored training in a rich scientific environment that includes both CHOP and University of Pennsylvania research communities.

This position offers the opportunity to work in the very early-onset inflammatory bowel disease (VEO-IBD) research group at The Children's Hospital of Philadelphia (CHOP). The VEO-IBD Program is a multidisciplinary program that includes Judith Kelsen, MD pediatric gastroenterologist and program director, Marcella Devoto, PhD, genetic epidemiologist, Noor Dawany, PhD, lead bioinformatician, Kathleen Sullivan, MD, PhD, Chief of Immunology and Edward Behren, MD, Chief of Rheumatology. This translational program is studying the unique genomic contribution to the disease through NGS and functional analyses. In addition, the group is studying the relationship between the genomic architecture and subsequent immune dysregulation with the microbiome in this population. This research group is interdisciplinary and highly collaborative.

The desired candidate must have a terminal degree (PhD) in computational biology, computer science, statistics, or related field. The postdoctoral fellow will be involved in the analysis of next-generation sequencing data related to pediatric inflammatory bowel disease research in the Division of Gastroenterology, Hepatology and Nutrition. The candidate is expected to be able to develop new algorithms, make sense of the data and construct predictive models for precision medicine applications. The postdoctoral fellow will assume responsibility for a specific, on-going research project under the joint direction/guidance of Dr. Kelsen, Dr. Dawany, Dr. Devoto and Dr. Taylor, head of the Bioinformatics Group in the Department of Biomedical and Health Informatics. The postdoc experience will serve to extend, refine and enhance skills necessary for professional and career development, and will enable the individual to broaden his/her scientific background by acquiring new research capabilities. It is expected that this individual will conduct independent scholarly research, and will contribute directly to the overall research goals of the project and the research group. Postdocs will be expected to participate in project planning, recording and interpretation/evaluation of data, and communication of results. The successful candidate is also expected to demonstrate basic scientific knowledge of cell biology, molecular biology, and/or immunology.

Postdocs will also be expected to acquire technical and manuscript/grant writing skills; and participate in seminars, lectures, poster sessions and presentations at national meetings. Postdoctoral fellows also may be required to develop new methods and protocols for research, and assist with the development of other research projects in the lab.


PhD in computational biology, computational science, statistics, or mathematics, engineering, genomics/genetics or related fields
UNIX/LINUX and high performance computing experience
Proficiency in R or similar commonly used statistical languages
Basic proficiency with Python, Perl, or other languages
Values research integrity and collaborative research
Strong research skills
Effective problem solving/critical thinking skills
Ability to work independently and with a strong work ethic
High level of motivation
Excellent communication/interpersonal skills
Ability to exercise discretion and judgment

All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption.

The Children's Hospital of Philadelphia is committed to providing a safe and healthy environment for its patients, family members, visitors and employees. In an effort to achieve this goal, employment at The Children's Hospital of Philadelphia, other than for positions with regularly scheduled hours in New Jersey, is contingent upon an attestation that the job applicant does not use tobacco products or nicotine in any form and a negative nicotine screen (the latter occurs after a job offer).

The Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.