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Postdoctoral Fellow (Synthetic Biology/Yasuo Yoshikuni's Group)

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POST DATE 9/2/2016
END DATE 10/28/2016

Lawrence Berkeley National Laboratory Berkeley, CA

Company
Lawrence Berkeley National Laboratory
Job Classification
Full Time
Company Ref #
82855
AJE Ref #
576076420
Location
Berkeley, CA
Experience
Entry Level (0 - 2 years)
Job Type
Regular
Education
Doctoral Degree

JOB DESCRIPTION

APPLY
Berkeley Lab is Bringing Science Solutions to the World, and YOU can be a part of it!

In the world of science, Lawrence Berkeley National Laboratory (LBNL) is synonymous with "excellence." That's why we hire the best - whether in research, science or operations. This is a great opportunity to bring your top-notch skills to bear in support of world-class scientific research that addresses national and global challenges!

Position Summary:

The Department of Energy Joint Genome Institute (DOE JGI, a division of Berkeley Lab) has an exciting opportunity available for a Postdoctoral Fellow. As part of a large multidisciplinary research program at the DOE JGI that is relevant to the DOE mission area, we seek to develop potent plant growth promoting rhizobacteria (PGPR), leveraging synthetic biology. This position directly reports to the Synthetic Biology - Pathway Engineering Group Lead.

Specific Responsibilities:

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Developing PGPR, leveraging synthetic biology:

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Discover novel secondary metabolites with PGP traits.
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Computationally analyze genomic and transcriptomic data and identify genes and biosynthetic clusters responsible for production of these secondary metabolites using experimental and bioinformatics tools.
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Construct design via codon optimization and refactoring.
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Produce these secondary metabolites and analyze via LCMS.
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Extract, isolate (HPLC), characterize and elucidate structure (MS & NMR) of bioactive secondary metabolites.

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Construct building (DNA synthesis and assembly).
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Transformation into heterologous host strains (primarily, rhizobacteria).
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Optimize production conditions for these secondary metabolite.
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Perform 16S rDNA sequencing.
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Prepare DNA and RNA samples for sequencing analyses.
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Summarize experimental results and present them at group meetings.
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Keep precise and detailed laboratory notebooks.
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Manage relationships with our collaborators.

Required Qualifications:

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Ph.D. degree in relevant fields such as Microbiology, Natural Products Chemistry, Metabolic Engineering, Synthetic Biology, or Computational Biology.
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Strong motivation to contribute to develop the areas of research under the DOE mission.
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Detailed knowledge in microbial genetics, metabolism, and physiology.
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Ability to successfully work in a dynamic team environment.
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Strong written and oral communication skills.

Additional Desired Qualifications:

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Experience in secondary metabolite extraction, isolation and structure elucidation (HPLC, LC-MS, NMR analysis).
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Experience in molecular biology techniques (molecular cloning, DNA extraction, PCR, RT-PCR, gel electrophoresis, genome sequencing, and RNA sequencing).

The posting shall remain open until the position is filled.

Notes:

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This is a 1 year postdoctoral appointment with the possibility of renewal based upon satisfactory job performance, continuing availability of funds and ongoing operational needs. You must have less than 3 of years paid postdoctoral experience. Salary for Postdoctoral positions depends on years of experience post-degree.
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This position requires completion of a background check.
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Salary will be predetermined based on postdoctoral step rates.
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DOE Joint Genome Institute (JGI) 2800 Mitchell Dr., Walnut Creek, CA

Berkeley Lab understands the postdoctoral experience in a research environment is unique. We are committed to the growth and development of early career researchers in pursuit of becoming next generation scientists and engineers. Read about the excellent postdoctoral benefits at Berkeley Lab.

Berkeley Lab addresses the worlds most urgent scientific challenges by advancing sustainable energy, protecting human health, creating new materials, and revealing the origin and fate of the universe. Founded in 1931, Berkeley Labs scientific expertise has been recognized with 13 Nobel prizes. The University of California manages Berkeley Lab for the U.S. Department of Energys Office of Science.

Equal Employment Opportunity: Berkeley Lab is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. Berkeley Lab is in compliance with the Pay Transparency Nondiscrimination Provision under 41 CFR 60-1.4. Click here to view the poster and supplement: "Equal Employment Opportunity is the Law.