Research Associate, Protein Chemistry

This job is no longer active. View similar jobs.

POST DATE 9/3/2016
END DATE 10/28/2016

Five Prime Therapeutics, Inc. South San Francisco, CA

Company
Five Prime Therapeutics, Inc.
Job Classification
Full Time
Company Ref #
360620
AJE Ref #
576082219
Location
South San Francisco, CA
Experience
Entry Level (0 - 2 years)
Job Type
Regular

JOB DESCRIPTION

APPLY
div id="contentwrapper" p strong Five Prime Therapeutics, Inc.  /strong (NASDAQ: FPRX) is a publicly traded, clinical-stage biotechnology company focused on discovering and developing innovative immuno-oncology protein therapeutics for patients with serious unmet medical needs. Five Prime has entered into strategic collaborations with leading global pharmaceutical companies and has promising product candidates in clinical and preclinical development. /p p We currently have three protein therapeutics in clinical trials: /p ul li FPA008: a monoclonal antibody that inhibits the CSF-1 receptor and is being studied in multiple tumor settings and pigmented villonodular synovitis (PVNS) /li li FPA144: a monoclonal antibody targeting FGFR2b for selected gastric cancers /li li FP-1039: a FGF ligand trap for mesothelioma /li /ul p On the strength of our unique discovery platform and capabilities, we have entered into strategic collaborations with leading global pharmaceutical companies.  We currently have three active research collaborations with Bristol-Myers Squibb, GlaxoSmithKline and UCB Pharma, S.A. /p p Five Prime is committed to innovation and outstanding science to develop effective new drugs for the treatment of severe diseases. These values are reflected in our people and our products. We value our culture of openness, collaboration and productivity. Discover more about FivePrime at a href="http://www.fiveprime.com" www.fiveprime.com /a . /p h2 The Position /h2 p Currently, we are seeking a highly motivated Research Associate to join our Protein Chemistry Department. The successful candidate will become a member of an exciting research team responsible for the production and characterization of human proteins in order to identify novel therapeutics and therapeutic targets.   In addition, the candidate will be involved in the development of new technologies to accelerate the discovery of protein therapeutics. /p h2 Responsibilities /h2 ul li Transient and stable mammalian protein production and purification of antibodies, ECD-Fcs, and untagged secreted proteins. /li li Characterization of protein products, determination of purity and aggregation levels to provide the highest quality therapeutics for in vitro and in vivo functional studies /li li Technology innovation that involves the design and implementation of robotic protein production and purification methodologies applicable to the entire FivePrime Protein Library /li li Development and high throughput application of protein-protein binding assays that include ELISAs, AlphaLISA, and interferometry-based screens /li /ul