Research Associate/Senior Research Associate
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Our Mission is to accelerate the discovery and development of novel medicines using innovative cell-based disease models. Our core technology is based on a decade of work at the Stanford University School of Medicine. We specialize in the generation of patient-specific stem cells and the subsequent derivation of innovative disease models. Our unique access to patient populations and strength in cell biology has enabled the development of a suite of inherited heart disease models that can now be used in investigating disease mechanisms, drug discovery, and personalized medicine.
We are seeking an independent and motivated research associate to join a growing scientific team focused on human induced pluripotent stem cell (iPSC) derivation, cardiac differentiation and cardiac disease modeling. This position requires expertise in reprogramming and routine culturing of iPSCs, characterization and differentiation of these cells, as well as standard molecular biology procedures, immunofluorescence microscopy, cellular cryopreservation and cell banking. The candidate must demonstrate a thorough knowledge of experimental design, underlying scientific principles, and the ability to independently assess results.
Successful candidates will be expected to:
Carry out reprogramming of human somatic cell into induced pluripotent stem
Maintain reprogramed iPS cell lines in culture
Conduct iPS cell characterization using basic molecular techniques
Cryopreserve and bank newly derived iPS cell lines
Differentiate iPS cell lines into functional cardiomyocytes (CMs)
Conduct CM characterization using basic molecular techniques
Maintain excellent quality control records
Provide basic lab support as needed
Maintain stock inventory for lab supplies
Ensure equipment maintenance
Provide training to other staff members in the area of stem cell culture
Troubleshoot assays and identify root cause to solve scientific problems.
Contribute ideas and suggestions to improve standard laboratory techniques,
protocols and processes.
Maintain professional expertise through familiarity with current scientific
literature and competitor products.
Comply with ethical, legal, and regulatory requirements and company safety
regulations and procedures.
May be required to perform other related duties as assigned by leadership.
Position exercises judgment within broadly defined practices and policies. The individual must be able to judge cell culture progress and quality. Position requires the individual to perform the duties listed above with only general direction from the Director. The person will understand the importance of the role in relationship to the company s values and business objectives. Excellent verbal, written communication and presentation skills are essential. This job will require a moderate degree of complexity. Focus will primarily be in the cell culture laboratory.