Research Engineer - Ott lab (Tissue Engineering)

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POST DATE 9/16/2016
END DATE 6/8/2017

Massachusetts General Hospital(MGH) Boston, MA

Boston, MA
AJE Ref #
Job Classification
Full Time
Job Type
Company Ref #
Entry Level (0 - 2 years)



The engineer will work with the Principal Investigator and be a central team member of several projects where s/he will provide critical engineering planning and analyses. Will design and develop devices, fixtures and test setups, including in vitro testing, to support tissue engineering research. Identifies and submits purchasing requests for materials in a cost effective manner. Creates and updates project documentation. Prepares reports and may make presentations. Ensures all work meets engineering and project standards. Utilizes all equipment safely and appropriately.


Identify project specifications in conjunction with Principal Investigator, establishing goals, time lines, operational requirements, materials, benchmarks and other project needs.

Investigate and evaluate methods and materials for each project and make recommendations to leadership.

Obtain and maintain scientific and technical knowledge needed to support overall research and individual studies. Utilize this knowledge in the development of tools, fixtures, devices, processes and in meeting other engineering objectives.

Plan, design, test, revise and maintain equipment needed for laboratory and individual studies. Equipment includes but is not limited to prototypes, fixtures, tools and medical devices.

Cost effectively purchase supplies and parts according to policies and within budget.

Document and maintain files on all designs and products.

Work proactively to resolve any malfunctions and upgrades. Work cooperatively with hospital staff, vendors and leadership to identify and resolve deficiencies, locate or build alternatives and otherwise support the research in a timely and effective manner.

Track, document and analyze all project related data and information, including but not limited to performance of materials, design and equipment. Prepare reports for leadership. Make presentations at staff meetings and to research leadership as needed. May author or contribute to department research articles and papers.

Identifies and follows all regulatory codes and operational directions governing the operation and maintenance of electrical, electronic and other equipment used during the work conducted on all projects. Works safely with all equipment, using personal protective equipment properly, also works safely within research laboratory conditions.

Current projects include:

* Development and prototyping of a perfusion-ventilation bioreactor for the preservation of donor lungs, and long-term culture of bioengineered lungs of small animal and human scale.

* Development of vascularized scaffold for tissue engineered lung. Scaffold includes vascular network optimized with computational fluid dynamics analysis. Other portions of scaffold include alveolar chamber for gas flow and interface between blood inflow and outflow as well as oxygen inflow and outflow. A skin to oxygen tubing interface is also a critical component under development

* Optimizing culture methods of tissue engineered lungs of small animal and human scale.


Knowledge of engineering technology skills including mechanical engineering design, computer aided drafting, specifically with Solidworks, finite element analysis and computational fluid dynamics analysis.

Knowledge of biological processes, terminology and general science as gained from laboratory studies is needed.

Computer skills, including Word, Excel and Powerpoint.

Good analytical, organizational and communications skills to clearly summarize data to communicate methods used, results, and conclusions for discussion in lab meetings and other forums.

Ability to manage project schedules for the delivery of program objectives.

Ability to execute all work independently, including research related, in a highly multidisciplinary team environment.
Is knowledgeable and compliant in all hospital, State and Federal regulatory requirements, including hospital policy and procedures (where applicable to the performance of the job), Joint Commission on Accreditation of Healthcare Organizations (JCAHO), and Health Insurance Portability and Accountability Act of 1996 (HIPAA).

Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged.