September 13, 2016

Research Fellow

Mass General Physicians Organization(MGPO) - Boston, MA

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  • Company
    Mass General Physicians Organization(MGPO) Mass General Physicians Organization(MGPO)
  • Location
    Boston, MA
  • Job Type
  • Job Classification
    Full Time
  • Experience
    Entry Level (0 - 2 years)
  • Education
    Doctoral Degree
  • Company Ref #
  • AJE Ref #
  • Hours/Week

Job Description


A research position in Molecular Biophysics and Structural Biology is available immediately at the Department of Molecular Biology, Massachusetts General Hospital. This is an appointment in the group of Dr. Luke Chao. The successful candidate will use methods including but not exclusive of biochemistry, structural biology (Electron Microscopy and X-ray Crystallography) and/or fluorescence microscopy to study mechanisms of organelle homeostasis by macromolecular assemblies. In addition to excellent research opportunities, the unique placement of the position will allow the candidate to acquire the experience of working in a multidisciplinary team.

Recent advances in the fields of electron microscopy (direct electron detectors and computational algorithms) and single molecule fluorescence poise us at an exciting moment for discovery. The potential for capturing conformational and compositional heterogeneity make it an incredibly exciting time for those interested in visualizing molecular mechanisms that drive cell fate. In reconstituting ever more complex multi-component systems, there is also great potential to describe kinetic mechanisms underlying fundamental processes.

What awaits you: a dynamic fast-paced environment where your versatility and curiosity will be rewarded. A successful candidate will take on troubleshooting challenging systems, contribute to existing projects and lead new projects.

The level of the position will be determined based on the candidates qualifications, and is expected to be at the level of Postdoctoral Researcher. Initial appointment will be for one year with the possibility of extension based on progress evaluation.

The ideal candidate will have:

* A Ph.D. in Biochemistry, Molecular Biology, Biophysics, Chemistry or a related field

* Experience in biochemistry or molecular biology

* Experience with membrane protein purification and characterization, a plus

* Background in structural biology or fluorescence microscopy

* Track record of publications in peer-reviewed journals

* Experience with UNIX/Linux operating systems

* Excellent communication skills and willingness to work in a multidisciplinary team

Massachusetts General Hospital, which is a teaching affiliate of Harvard Medical School, provides an outstanding environment for biomedical research. The successful candidate will have ample opportunities to work with the top scientists in the field.

Please send your CV, a brief statement of research interests, your best paper(s) in PDF format (no more than three), and contact information for three references to

Review of applicants will begin immediately and will continue until the position is filled.