Research Fellow

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POST DATE 9/13/2016
END DATE 6/9/2017

Mass General Physicians Organization(MGPO) Boston, MA

Boston, MA
AJE Ref #
Job Classification
Full Time
Job Type
Company Ref #
Entry Level (0 - 2 years)
Doctoral Degree



A research position in Molecular Biophysics and Structural Biology is available immediately at the Department of Molecular Biology, Massachusetts General Hospital. This is an appointment in the group of Dr. Luke Chao. The successful candidate will use methods including but not exclusive of biochemistry, structural biology (Electron Microscopy and X-ray Crystallography) and/or fluorescence microscopy to study mechanisms of organelle homeostasis by macromolecular assemblies. In addition to excellent research opportunities, the unique placement of the position will allow the candidate to acquire the experience of working in a multidisciplinary team.

Recent advances in the fields of electron microscopy (direct electron detectors and computational algorithms) and single molecule fluorescence poise us at an exciting moment for discovery. The potential for capturing conformational and compositional heterogeneity make it an incredibly exciting time for those interested in visualizing molecular mechanisms that drive cell fate. In reconstituting ever more complex multi-component systems, there is also great potential to describe kinetic mechanisms underlying fundamental processes.

What awaits you: a dynamic fast-paced environment where your versatility and curiosity will be rewarded. A successful candidate will take on troubleshooting challenging systems, contribute to existing projects and lead new projects.

The level of the position will be determined based on the candidates qualifications, and is expected to be at the level of Postdoctoral Researcher. Initial appointment will be for one year with the possibility of extension based on progress evaluation.

The ideal candidate will have:

* A Ph.D. in Biochemistry, Molecular Biology, Biophysics, Chemistry or a related field

* Experience in biochemistry or molecular biology

* Experience with membrane protein purification and characterization, a plus

* Background in structural biology or fluorescence microscopy

* Track record of publications in peer-reviewed journals

* Experience with UNIX/Linux operating systems

* Excellent communication skills and willingness to work in a multidisciplinary team

Massachusetts General Hospital, which is a teaching affiliate of Harvard Medical School, provides an outstanding environment for biomedical research. The successful candidate will have ample opportunities to work with the top scientists in the field.

Please send your CV, a brief statement of research interests, your best paper(s) in PDF format (no more than three), and contact information for three references to

Review of applicants will begin immediately and will continue until the position is filled. Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged.