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Scientist, Biologics Discovery & Protein Sciences, New Venture Labs

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POST DATE 9/11/2016
END DATE 10/27/2016

Moderna Therapeutics Cambridge, MA

Cambridge, MA
AJE Ref #
Job Classification
Full Time
Job Type
Company Ref #
Mid-Career (2 - 15 years)
Doctoral Degree


Scientist, Biologics Discovery & Protein Sciences, New Venture Labs


The Scientist, Biologics Discovery & Protein Sciences, New Venture Labs will be responsible for developing a new capability of therapeutic protein discovery. The activities will include structural biology, generation of antibody libraries from B-cells and in vitro discovery techniques to select, design and characterize proteins for in vivo therapeutic activity. Evaluate the selected therapeutic proteins in a collaborative team to define their pharmacokinetic and pharmacodynamics properties in the appropriate therapeutic area.


* Generate antibody and therapeutic protein libraries utilizing cell-based screening technologies to isolate molecules of therapeutic interest

* Set up in house cell based screening capabilities to select and optimize key parameters as appropriate (i.e. affinity, diverse epitope recognition, stability)

* Serve as a technical expert in cell-based screening technologies providing support to multiple projects and select candidate molecules for therapeutic development

* Identify, manage and contribute to external collaborations relevant to cell-based screening or other screening technologies

* Maintain accountability for project success and results delivery

* Contribute to scientific and strategy discussions to advance and enhance the scientific platform and product candidates

* Communicate research and development findings internally and externally


* Ph.D. in protein engineering, biochemistry, molecular biology, or related field

* 5+ yrs experience in the discovery of therapeutic proteins, engineering and antibody selection

* Expertise in therapeutic antibody discovery and engineering experience

* Therapeutic antibody discovery from a variety of species

* Single cell PCR, B-cell culture, FACS sorting, cell-based assay development

* A proven track record


* Ph.D. in biological sciences

* Strong written and oral communication skills, comfort with senior management interactions

* Positive team building and teamwork skills: Innate ability to influence, lead and inspire people, within function and beyond functional/company boundaries

* Strong skills in molecular, cellular and immunology


* Scientific rigor & commitment to excellence and innovation

* Must be a team player who thrives in a collaborative environment with ability drive a project forward with independently and as part of a cross-functional team

* Outcome-oriented and attentive to details

* Flexibility / Adaptability to frequent change

* Effective communication, both written and verbal

* Personal and shared accountability