Scientist, Cancer Immunotherapy

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POST DATE 9/9/2016
END DATE 10/10/2016

Fate Therapeutics, Inc. San Diego, CA

Company
Fate Therapeutics, Inc.
Job Classification
Full Time
Company Ref #
360758
AJE Ref #
576125542
Location
San Diego, CA
Experience
Entry Level (0 - 2 years)
Job Type
Regular

JOB DESCRIPTION

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Fate Therapeutics is seeking a highly motivated and innovative research investigator with significant expertise in immuno-oncology and NK cell biology to join a dynamic team dedicated to the discovery and development of novel cellular therapies for the treatment of cancer. The position will oversee and execute studies for the development of programmed hematopoietic cellular therapeutics, with an emphasis on NK cell therapeutics. The candidate must have a comprehensive understanding of NK cell / T cell immunology and oncology combined with practical and technical experience in mammalian cell culture including but not limited to isolation and phenotypic characterization of human and/or mouse NK cells, extensive technical experience in multi-color flow cytometry (FACS) and MACS enrichment, NK cell or T cell activation/cytotoxic killing assays, cytokine profiling and cell isolation techniques. The successful candidate will develop and conduct functional assays and models to validate the biological properties and therapeutic potential of NK cell therapeutics generated by Fate s novel small molecule programming and induced pluripotent stem cell platforms.

Responsibilities include
Independently develop experimental plans and successfully execute research timelines to meet program and corporate objectives
In depth characterization of NK cell therapeutic candidates in various tumor models
Identification and implementation of novel approaches to modulate NK cell and T cell differentiation and effector function
Establish and run in vitro culture systems and in vivo animal models to validate the efficacy and persistence of candidate cell therapeutics
Participation in cross-functional teams to support the development of genetically-engineered NK and T cell therapeutics
Initially, manage a small group of scientists with opportunity to expand