Scientist I, Fluorescent Microscopy & Bioanalysis

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POST DATE 9/15/2016
END DATE 10/23/2016

MedImmune, LLC Mountain View, CA

Company
MedImmune, LLC
Job Classification
Full Time
Company Ref #
360907
AJE Ref #
576179454
Location
Mountain View, CA
Experience
Entry Level (0 - 2 years)
Job Type
Regular

JOB DESCRIPTION

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The Clinical Immunology & Bioanalysis (CIB) group in the Translational Sciences Department is seeking a highly motivated individual with strong background in fluorescent microscopy and cell biology to join as Scientist I. The candidate will provide bioanalytical support to pre-clinical and clinical development of biopharmaceuticals. The candidate will be responsible for characterization of receptor-mediated internalization and trafficking to support PK-PD modeling, dose projection and mechanism of drug action. The candidate will utilize state-of-the art confocal fluorescent imaging instrumentation and develop cell-based assays and quantitative image analysis algorithms. The candidate will be also involved in development, validation and execution of cell-based and biochemical assays for evaluation of pharmacodynamics (PD) activity and detection of neutralizing anti-drug antibodies (Nab) to support programs. The candidate will be a key person for fluorescence microscopy, imaging flow cytometry and quantitative image analysis. The candidate is expected to work with minimal supervision and will report to CIB Principal Scientist. p /p ~BSP p /p