Scientist/Senior Scientist, Molecular Biology
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POST DATE 9/18/2016
END DATE 10/23/2016
South San Francisco, CA
JOB DESCRIPTIONAPPLY The Company:
This is an exciting opportunity to be a key contributor at ChemPartner, a leading Shanghai based Contract Research Organization specializing in drug discovery services. As more and more Pharma and Biotech companies look for alliance partners to increasingly provide intellectual contributions and exceptional technical expertise, ChemPartner is uniquely positioned to not only be a LifeScience CRO, but to be a pharmaceutical alliance partner. With a team of over 2000 experienced scientists, hundreds of western-trained pharmaceutical industry leaders, and experienced Pharmaceutical Executive Leadership at the helm, ChemPartner is aligned and dedicated to technically and strategically accomplish the research initiatives of Pharma and Biotech companies from around the world.
This position will be based at ChemPartner s South San Francisco facility with occasional trips to Shanghai, China.
We are seeking a motivated scientist/senior scientist with expertise in constructing mammalian and bacterial expression vectors, including codon and signal peptide optimization to improve protein expression. The individual will focus on high expression vector construction using various molecular biology and protein engineering tools and will be involved in selecting, evaluating and characterizing vectors for improved antibody expression from mammalian cell lines. The successful candidate will be resourceful, integrating ideas from diverse sources, have the ability to articulate a plan, proficiently troubleshoot issues and reduce improved methods to practice. She/he will have strong skills in organization, communication, technical troubleshooting, multi-tasking and thrive in a highly collaborative environment.
ChemPartner offers a strong compensation package including salary, 401(k) and a comprehensive benefits package.
Develop transient and/or stable cell lines for therapeutic protein expression in an industrial setting
Proactively seek, research, propose and evaluate new protein expression technologies to enhance productivity and yield
Independently review literature, design experiments, analyze data, document procedures and data thoroughly in notebooks, write reports and present data to group members
Develop new techniques, perform troubleshooting, draft experimental protocols and train group members in Shanghai on improved methods
Perform CHO or other mammalian cell culture and related assays, including but not limited to: cell transfection, stable cell line generation, limited dilution cloning, evaluation of protein production from transient and stable expression cell lines, cell banking, ELISA, Flow cytometry, HPLC, molecular cloning and gene expression
Assist group members in Shanghai with technical troubleshooting
May collaborate with other functional groups in Shanghai on projects, communicate with clients and present at internal team and external client meetings