Clinical Outreach Manager - Cancer Cell Line Factory

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POST DATE 9/17/2016
END DATE 3/23/2017

Broad Institute Cambridge, MA

Cambridge, MA
AJE Ref #
Job Classification
Full Time
Job Type
Company Ref #
Mid-Career (2 - 15 years)
Bachelors Degree


Job Description:

The Broad Institute of Harvard and MIT is looking for an exceptional candidate for a unique position as the Cancer Cell Line Factory (CCLF, project's Clinical Outreach Manager. This position affords the exciting opportunity to be part of a new and rapidly growing research effort at the Broad Institute aiming to create hundreds of new models of cancer each year directly from patient samples, with full genomic and clinical characterization, to fuel the study of cancer dependencies at scale. Since the paucity of cell line models has severely blunted research in cancer, achieving this project goal will catalyze new directions in biomedical research with potential for global impact.

The CCLF project is a collaboration involving over 50 individuals and 20 laboratories that depends on deep coordination between laboratory and clinical sites. This individual will be responsible for working with clinical colleagues to establish and refine robust local, regional, national and international biospecimen acquisition pipelines. He/she will travel locally to clinical sites and work closely with hospital staff to ensure biospecimen and clinical data are acquired on pre-approved timelines. He/she will also partner closely with the Laboratory cell model derivation team at the Broad Institute to ensure that milestones and timelines are met and that results and issues are promptly communicated back to clinical collaborators and external partners.

He/she will coordinate new direct-to-patient online sample acquisition projects that have been recently launched in collaboration with external research foundations and internal Broad teams. Throughout, relationship management (with scientists, clinicians, funders and patients) will be a primary focus as this person will serve as the key liaison between collaborators, the CCLF Operations and Innovation teams. Project risk identification and mitigation will be a part of the responsibilities.

In addition, the successful candidate will work closely with compliance and regulatory and business development teams to optimize inter-institutional alignment and patient protection. He/she will work closely with external funding agencies to track project progress, prepare milestone reports and ensure that milestones are achieved. Critically, he/she will identify problems and bottlenecks and propose and implement solutions. The successful candidate is expected to work in close collaboration with the CCLF Operations and Scientific Leaders, trainees, computational biologists and Project Principal Investigators.

The Broad Institute provides a vibrant research environment with close links to top academic institutions across the Boston Area and provides the potential for your contributions to be used and recognized worldwide.


Clinical Relationship Development

* Serves as the key project liaison for collaborators, including senior scientists and principal investigators, in a variety of clinical settings.

* Effectively communicates with scientists, clinical research coordinators, pathologists and technicians to collect biospecimens, track samples, share project status, updates and results.

* Develops and communicates comprehensive project plans including scope, goals, resource requirements, risk analysis and implementation strategies

* Proactively identifies critical blocking issues, proposes solutions and works with others to implement solutions.

* Drives the use of best practices for project management and technology solutions to provide timely updates to all project partners

Laboratory Project Management

* Acquires high quality biospecimens by coordinating closely with collaborators, and ensures sample-sourcing bottlenecks are addressed proactively.

* Coordinates with laboratory team to troubleshoot laboratory processes. Suggests possible improvements as needed and works with others to implement solutions.

Project Reporting and Evaluation

* Tracks project status and dependencies to ensure projects meet milestones and ensure scientific progress.

* Compiles scientific reports, oral presentations and summaries of analyses to share with collaborators, funding agencies and other stakeholders.

* Works closely with others to ensure that the IRB consent process is optimized for both well-studied as well as underrepresented populations and that MTA and intellectual property inter-institutional negotiations are completed efficiently.


* Interpersonal and relational skills: The candidate must effectively discuss, negotiate and influence current and potential collaborators by developing strong working relationships, fostering teamwork and building trust with all stakeholders.

* Project management skills: The candidate must be able to manage a complex initiative with multiple moving components, assess possible options and identify the best solutions for a given project or scenario.

* Scientific skills: The candidate will need a solid understanding of cancer genomics, patient-derived models and/or the clinical setting to understand both the high level scientific objectives of each project as well as assist in laboratory process improvement in consultation with the CCLF Operations team.

* Problem-solving skills: The candidate must be able to proactively anticipate issues before they arise, recognize shortcomings and suggest effective solutions.

* Time-management skills: The candidate must be able to perform multiple tasks at the same time to ensure that the project meets deadlines and goals.


* Life sciences degree required. Either BS with 5+ years of direct project management experience or MS/PhD with 2+ years of project management experience needed.

* Excellent communication, interpersonal skills and alliance management experience are required.

* 2+ years experience managing complex, inter-institutional projects with multiple milestones, regulatory components and government agency experience required.

* Project management in a clinical setting or evidence of formal project management training desirable.

* Strong track record of critical contributions to successful scientific projects.

* Demonstrate a high level of initiative, ability to work independently and in cross-functional teams.

EOE / Minorities / Females / Protected Veterans / Disabilities