Senior Microscopist 630486 (NCI)

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POST DATE 8/13/2016
END DATE 11/12/2016

Leidos Biomedical Research, Inc. Frederick, MD

Frederick, MD
AJE Ref #
Job Classification
Full Time
Job Type
Company Ref #
Entry Level (0 - 2 years)


Leidos Biomedical Research, Inc. (LBRI), a wholly owned subsidiary of Leidos, operates the Frederick National Laboratory for Cancer Research (FNLCR). FNLCR is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI). It is the only FFRDC dedicated to biomedical research. Through its status as an FFRDC, FNLCR provides NCI and others with a unique national resource to accelerate the development and delivery of effective preventive, diagnostic, and therapeutic products for cancer and AIDS.
The breadth of FNLCR s activities spans the research and development spectrum, including investigator-initiated, hypothesis-driven research into cancer and AIDS; advanced technology programs focused on genetics and genomics, proteins and proteomics, imaging, nanotechnology, bioinformatics, and laboratory animal sciences; clinical operations in support of NCI and National Institute of Allergy and Infectious Diseases (NIAID)-sponsored clinical trials, as well as NCI drug discovery and development efforts; and management and operations of biopharmaceutical development and manufacturing programs under current Good Manufacturing Practice conditions for NCI and NIAID. Administrative, procurement, financial, safety, and facilities support is provided to these R&D activities through state-of-the-art business processes. LBRI has approximately 1,900 employees and manages an annual operating budget of approximately $450M.
For more information about Leidos Biomedical Research Inc., please visit our webpage at

The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish National Cancer Institute (NCI) research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community. The National Cancer Institute, NIH has committed to establishing a national cancer research community-accessible cryo-EM user facility that will be managed and operated by CRTP/FNLCR. The purpose of the facility is to enable the collection of high quality cryo-EM images, with minimal delay between request for access and data collection from prospective users who can show that they have quality specimens ready to image at high resolution. This facility will begin to address the pressing national and regional need that US structural biologists have access to advanced microscopes capable of supporting high resolution cryo-EM studies.

The Senior Microscopist will: 1) oversee a scientific team that includes a Scientific Project Manager and 1-2 junior Microscopists, 2) oversee organizational infrastructure for user facility, 3) design and maintain data storage and transmission, 4) run and oversee maintenance of cryo-EM equipment that currently includes a Titan Krios microscope, 5) work with users to acquire cryo-EM data, organize and maintain data storage and transfer to users, 6)work closely with the Project Manager to communicate with users about shipping, data, any necessary technical details and scheduling, and 7) work with the Program Manager to provide quarterly reports to NCI.

While initial training on microscope operation will be provided to the successful candidate, he/she will be responsible for training new team members in use of cryo-EM equipment after the initial period.