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POST DATE 9/2/2016
END DATE 11/19/2016
JOB DESCRIPTIONMilliporeSigma is the North American life science brand of Merck KGaA, Darmstadt, Germany a leading science and technology company. It offers a broad range of innovative products and services to biotech and pharmaceutical drug therapies businesses. Through dedicated collaboration with the scientific and engineering communities, and as one of the top three R&D investors in the life science tools industry, the brand serves as a strategic partner to customers and helps advance the promise of life science.
SCOPE OF RESPONSIBILITY:
Design, execute and analyze studies related to client projects as well as internal projects. Hands-on
involvement for upstream production downstream purification of viral vectors. Client interaction.
PURPOSE OF THE POSITION
The Scientist will be responsible for assigned projects to generate viral vector products. The Scientist will
be the main lead (or co-lead) and scientific resource for such projects in the Process Development
Department. The Scientist is responsible for understanding the scope of work, generate all related
documentation (as required), perform the studies, generate data, generate product, coordinate testing
with Analytical Services, analyze results and create a development report.
The Scientist is expected to interact with clients throughout the project (providing updates and troubleshooting when needed). The
hired person is expected to interact with the Tech Transfer team and the Manufacturing team to facilitate
the transfer of the process from Process Development into GMP Manufacturing. The Scientist may be
involved in Process characterization and Process Validation studies as part of commercialization.
ESSENTIAL JOB FUNCTIONS
Act as the lead scientist on new customer production projects or ongoing projects as needed.
Assist with new or ongoing projects as deemed necessary.
Liaise closely with client representatives to ensure their expectations are met or exceeded.
Generate timeline and ensure timely initiation and completion of all studies.
Generate Process Development Worksheets to serve as guidance for study execution as well as
means for real-time documentation.
Participate and/or drive Process transfer activities.
Assist in implementation of new technologies.
Participate in critical event / lab investigations / troubleshooting within Process Development and
liaise with Other team members in Process Development as well as Project Management to ensure
the significance of events is actively communicated to clients.
Lead by example, offer scientific coaching and mentoring to other staff members (training and
scientific support for ongoing projects).
Promote a culture of continuous improvement within Process Development.
Prepare and present (internally and externally) scientific data, abstracts, papers, posters, etc. to
advance the reputation of MilliporeSigma Carlsbad within the marketplace.
Track and trend key production parameters and recommend courses of action to address any
adverse trends and / or issues that arise.
Provide technical advice and support for client and regulatory interactions (audits, meetings,
teleconferences and inspections).
May perform other related duties as required and / or assigned.
MS in scientific discipline with 3 or more years relevant experience
BS in scientific discipline with 6 or more years relevant experience
Relevant working knowledge and hands-on experience in area executing and overseeing
technical projects and/or related studies (i.e. Virology, Molecular Biology, Cell Biology, etc.)
Preferred experience in specific area in the industry (i.e. viral vector production and purification).
Knowledge and Skills:
Hands-on skill set for aseptic technics in handling cell culture.
Hands-on experience of various platforms used for suspension cultures and adherent cultures
with emphasis on large scale cell culture using bioreactors.
Knowledge and hands-on experience of various approaches used for downstream purification
focusing on tangential flow filtration and chromatography.
Excellent verbal and written communication.
Excellent time management skills.
Highly collaborative as well as independent with high degree of initiative.
Good skills in applicable computer programs.
Good working knowledge of company commercial and financial strategies.
The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law. This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to his/her Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because he/she made a good faith report of discrimination.