Senior Research Associate, Molecular Pharmacology
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POST DATE 9/18/2016
END DATE 10/23/2016
South San Francisco, CA
JOB DESCRIPTIONReset Therapeutics is a startup biotechnology company that exploits circadian rhythm biology for the generation of novel pharmaceuticals. While Reset is agnostic to therapeutic area, current discovery programs target orphan diseases and unmet medical needs in metabolic and CNS disorders. Reset performs in vivo and in vitro biology and medicinal chemistry design in house and collaborates closely with various CROs for off-the-shelf and specialized functions critical to the discovery of high-quality clinical candidates. Reset is seeking a Senior Research Associate with significant experience in industrial pharmaceutical screening to help drive its drug discovery programs. The primary responsibility of this position is the implementation and performance of biochemical and cell-based assays for the robust screening of compounds. The successful candidate will join a team of scientists to assess novel therapeutics targeting protein constituents of the circadian molecular clock and its outputs.
MAJOR DUTIES AND RESPONSIBILITIES
Work closely other members of the Molecular Pharmacology team to develop and optimize target-based screening assays
Perform robust target-based screening of compounds to determine the potency of test compounds
Work closely with chemists and project leaders to track and escort sets of compounds through screening assays
Develop and implement assays to measure pre-clinical biomarkers for in vivo efficacy studies
Participate in the collaborative evaluation of new technologies
Contribute to overall laboratory operations
COMPENSATION AND BENEFITS
You will appreciate a competitive compensation package including excellent benefits (medical, dental, vision, 401k Plan, Life/disability insurance and more). You will enjoy a challenging work environment, amazing colleagues and the ability to make a difference.
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