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Senior Scientist-Protein Characterization

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POST DATE 9/18/2016
END DATE 10/23/2016

OncoMed Pharmaceuticals, Inc. Redwood City, CA

Redwood City, CA
AJE Ref #
Job Classification
Full Time
Job Type
Company Ref #
Entry Level (0 - 2 years)


Job Summary:
OncoMed Pharmaceuticals is developing novel biologic therapies for the treatment of cancer and currently has 7 clinical stage product candidates. This position is for a protein characterization scientist who will help to advance the OncoMed pipeline by defining product Critical Quality Attributes, developing test method for release and stability and supporting process development.

Under limited supervision, the Scientist's primary responsibilities involve the design, conduct and oversight of protein characterization studies. In addition, the candidate will be expected to perform some testing as needed in support of process development.

The job responsibility is within the Analytical Sciences group, reporting to the Director.

Define Critical Quality Attributes for both early and late phase clinical programs using a combination of chromatographic, electrophoretic and biophysical approaches
Perform forced degradation studies to support CQA assessment, process development and specification setting
Perform pre-formulation studies
Participate in comparability assessments for later stage programs
Establish working relationships with other groups within Research and Development to support the development of the OncoMed pipeline
Managing, Training and/or mentoring others
Provide support to upstream, downstream and formulation development as appropriate