Senior Scientist

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POST DATE 9/14/2016
END DATE 12/1/2016

MilliporeSigma Saint Louis, MO

Saint Louis, MO
AJE Ref #
Job Classification
Full Time
Job Type
Company Ref #
Entry Level (0 - 2 years)
Doctoral Degree


Development Chemist (O5) - PhD

Essential job functions:

The employee will work in a project-focused environment as a member of an active, multidisciplinary group responsible for manufacturing process development of new products and optimization of established manufacturing procedures. Responsibilities include designing and performing laboratory experiments, evaluating data, and communicating project results in order to meet the ultimate goal of creating a reliable manufacturing procedure. The employee will also be expected to aid in scale-up of his or her newly developed process to manufacturing scale, which may include writing manufacturing instruction, training operators, and troubleshooting process problems. Process development will be focused on the following: fermentation / cell culture, extraction of proteins from plant, animal, or bacterial sources, and protein purification.


This position requires a PhD in biochemistry, microbiology or a related discipline. A broad understanding of molecular biology and biochemistry lab techniques is essential, and includes the following: Protein purification and characterization, chromatography (IEX, HIC, SEC, etc.), enzymatic assay, recombinant protein expression, and microbial cell culture. Preference will be given to individuals that have experience with yeast, CHO, or other non-E. coli cell culture. Experience with automated chromatography systems (such as GE AKTA or Millipore K-Prime) and bioreactors / fermenters (such as Sartorius BIOSTAT), as well as knowledge of cell culture optimization techniques are highly desirable. Interpersonal, communication, organizational and computer skills are required.

MilliporeSigma is the North American life science brand of Merck KGaA, Darmstadt, Germany a leading science and technology company. It offers a broad range of innovative products and services to biotech and pharmaceutical drug therapies businesses. Through dedicated collaboration with the scientific and engineering communities, and as one of the top three R&D investors in the life science tools industry, the brand serves as a strategic partner to customers and helps advance the promise of life science.

The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law. This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to his/her Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because he/she made a good faith report of discrimination.


Millipore Corporation (Millipore) is a life science company. The Company provides products and services that help its academic, biotechnology and pharmaceutical customers advance their research, development and production In August 2009, the Company acquired BioAnaLab, a European-based services provider that specializes in the analysis of biologic drugs and vaccines.