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Chemical Proteomics/Mass Spectrometry Associate 10/11/2017

Pfizer Inc. La Jolla, CA

Location
La Jolla, CA
AJE Ref #
579731833
Job Classification
Full Time
Job Type
Regular
Company Ref #
375138
Experience
Entry Level (0 - 2 years)

JOB DESCRIPTION

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img src="https://counter.adcourier.com/YnJlbmRhLmJvd2xpbmcuNDkzODMuNDI0M0BwZml6ZXIuYXBsaXRyYWsuY29t.gif" p strong ROLE SUMMARY /strong br / br / Pfizer is seeking applications for a Scientist with mass spectrometry-based proteomics experience. Such a candidate will be a highly motivated and creative scientist with the desire to join and support proteomic capabilities for our oncology pipeline. This person will align with our Chemical Biology group enabling impact across the small molecule oncology portfolio from early exploratory target identification through the drug discovery pipeline and into early clinical development. br / br / The individual will support and aid in the development of innovative mass spectrometry platforms. Their work will enable quantitative chemical proteomics methodologies for a deeper understanding of our molecules and cellular targets. Relevant methodologies include but are not limited to: identification of novel oncology targets, small molecule target deconvolution, small molecule target occupancy studies using chemical probes, direct substrate identification and characterization, protein turnover studies, protein post-translation modification studies and small molecule-protein interactome analyses. strong ROLE RESPONSIBILITIES /strong /p ul li Apply quantitative protein mass spectrometry technologies for chemo-proteomics and general proteomics across the oncology portfolio. /li li Participate in all aspects of laboratory operations including sample preparation, running samples on the MS, data analysis and interpretation. /li li Development of methods for peptide separation and analysis. /li li Presenting and reporting data with follow up discussions for project teams including data impact and interpretation. /li li Complete and effectively manage multiple projects within timelines ensuring that all tasks and responsibilities are carried out according to high scientific and ethical standards. /li li Engage in collaborative and strategic partnerships with internal research teams to apply proteomics for oncology discovery, impacting all oncology research focuses including: Systems Therapeutics, Tumor Intrinsic Biology, Immuno-oncology and Epigenetics. /li /ul