PostDoc Fellow - Investigation of covalent inhibitors targeting non-catalytic lysines in disease-causing proteins

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POST DATE 2/20/2017
END DATE 4/23/2017

AstraZeneca Pharmaceuticals LP Waltham, MA

Waltham, MA
AJE Ref #
Job Classification
Full Time
Job Type
Company Ref #
Entry Level (0 - 2 years)


div class="overview-left" div class="job-location job-info" b Location: /b Waltham, Massachusetts, United States br /div b Job reference: /b R-003808 br br b Posted date: /b Mar. 10, 2017 br br ul style="margin-top:40px;" /ul /div br br div class="ats-description" itemprop="description" p At AstraZeneca, we believe in the potential of people who share our passion for science. By thinking boldly and working collaboratively to pursue discoveries beyond imagination, you’ll develop further and faster than you thought possible. We’ll complement your drive and determination to meet unmet patient needs around the world with the inspiration and opportunities to enhance your niche expertise and build your skills. So if you’re curious about what science can do, come and make a difference. /p p Cancer is one of the greatest challenges facing medical science today. In our Oncology Team, you’ll push the boundaries of science every day to overcome that challenge. We’ve been at the centre of some of the biggest breakthroughs in oncology. In lung cancer, for example, we‘ve brought together complementary expertise to aid discovery and accelerate development in new medicines through a variety of partnerships and initiatives. We’re also early adopters of new technologies to support innovation, including CRISPR, genome editing techniques and a next-generation sequencing platform for companion diagnostics in oncology. But we’re not stopping there. With a world-class pipeline and some of the best experts in the industry, we’re in a great position to develop even more innovative therapeutic approaches. br /p p b Main duties and responsibilities /b /p p A self-motivated chemist, you’ll work in a multidisciplinary setting carrying out cutting-edge research in rational design of covalent inhibitors targeting non-catalytic lysines. You will be responsible for designing and synthesizing covalent inhibitors towards disease causing proteins; investigating the properties of the resulting inhibitors; applying the learning in the drug discovery program; and communicating scientific finding in the internal/external science community. /p