PostDoc Fellow - Mechanism-based translation of drug pharmacokinetics across ethnic populations (Caucasians, Chinese

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POST DATE 2/20/2017
END DATE 4/23/2017

AstraZeneca Pharmaceuticals LP Waltham, MA

Company
AstraZeneca Pharmaceuticals LP
Job Classification
Full Time
Company Ref #
366200
Location
Waltham, MA
Experience
Entry Level (0 - 2 years)
Job Type
Regular
AJE Ref #
577594704

JOB DESCRIPTION

div class="overview-left" div class="job-location job-info" b Location: /b Waltham, Massachusetts, United States br /div b Job reference: /b R-003852 br br b Posted date: /b Mar. 10, 2017 br br ul style="margin-top:40px;" /ul /div br br div class="ats-description" itemprop="description" p At AstraZeneca we believe in the potential of our people and you’ll develop beyond what you thought possible. We make the most of your skills and passion by actively supporting you to see what you can achieve. We need great people who share our passion for science and have the drive and determination to meet the unmet needs of patients around the world. If you’re curious about what science can do, then you’re our kind of person br /p p You’ll be working in pharmacological and statistical modeling across all therapeutic areas, based in our Department of Quantitative Clinical Pharmacology at Waltham, MA. You’ll also be a member of the Interdisciplinary Program in Pharmacometrics, which links pharmacometric experts across the Scientific Core Platforms. /p p b Main duties and responsibilities /b /p p You’ll be working in pharmacological and statistical modeling across all therapeutic areas, based in our Department of Quantitative Clinical Pharmacology at Waltham, MA. You’ll also be a member of the Interdisciplinary Program in Pharmacometrics, which links pharmacometric experts across the Scientific Core Platforms. /p p You’ll perform literature searches and evaluate available clinical reports in different ethnicity, as well as collecting preclinical and clinical data for identified drugs. Then you’ll develop PBPK models and population pharmacokinetic models with the collected data and create an approach to compare the pros and cons of both methodologies and propose good practice based on your findings, validating your recommendation with emerging data. /p p This is an excellent opportunity to develop skills in clinical pharmacology, as well as pharmacometrics and its impact in the drug development process, particularly toward development in different ethnic populations. You’ll be collaborating with AstraZeneca scientists across the globe, as well as working independently, so you should be open to developing and sharing new ideas to improve or enhance current processes. You’ll also be actively engaged with both AstraZeneca and academic supervisors and will be encouraged to publish scientific papers describing your project findings and especially any novel method/approaches. /p