Principal Scientist - Computational Chemistry / Chemical Informatics 10/9/2017

Celgene Cambridge, MA

Company
Celgene
Location
Cambridge, MA
AJE Ref #
579715452
Job Classification
Full Time
Job Type
Regular
Company Ref #
375120
Experience
Entry Level (0 - 2 years)

JOB DESCRIPTION

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strong Other Locations: /strong US- MA- Cambridge P /p P strong Responsibilities will include, but are not limited to, the following: /strong /P ul li In close collaboration medicinal chemists and project teams, apply a wide variety of drug-design and computational chemistry methods to improve potency, selectivity, and ADME properties while minimizing toxicological risk. /li li Enhance our understanding of SAR and influence team strategy by assimilating and interpreting data using modeling and data-mining technologies. /li li Apply and develop new approaches for designing bioactive-relevant features using machine-learning, scoring functions, and multiple endpoint optimization methods. Maintain and develop working knowledge of contemporary computational chemistry methods and their use in ligand design and data analysis as applied to drug design projects. /li