Scientist I/II, Protein Characterization

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POST DATE 9/17/2017
END DATE 11/5/2018

MedImmune, LLC Gaithersburg, MD

Gaithersburg, MD
AJE Ref #
Job Classification
Full Time
Job Type
Company Ref #
Entry Level (0 - 2 years)


div div b Location: /b div span Gaithersburg, /span span Maryland, /span span United States /span /div /div span b Job reference: /b R-005426 /span br span b Posted date: /b Sep. 14, 2017 /span br ul style="margin-top:40px;" /ul /div div p If you’re inspired by the possibilities of science to change lives and you thrive when making brave decisions – join us. /p p /p p b span MedImmune /span /b span is the worldwide biologics research and development arm of AstraZeneca. Here, you’ll have the opportunity to make a difference in people’s lives every day. As one of the world’s premier biotechnology companies, our mission is centered on delivering life-changing products that advance world health, and help fight and cure disease.  As a Scientist I/II, in Gaithersburg, MD, you’ll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives. /p p /p p We’re constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We’re pioneering innovative research and exploring novel pathways across key therapeutic areas including oncology, respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines. And we’re industry-leading in immunology, protein engineering and translational science. We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules. /p p /p p MedImmune has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent. /p p /p p b span Main Duties and Responsibilities /span /b /p p You will be expected to design and execute detailed characterization of protein, including product variant isolation / enrichment and characterization, identification of protein degradation pathways, structure-functional correlation, and determination of critical quality attributes. You will be responsible for development and optimization of analytical methods and testing to progress development of therapeutic proteins.  Make detailed experimental observations, review and analyze data, and interpret experimental results.  You will author technical report and regulatory filings for clinical trials and marketing span applications. Provide /span cross-functional support to formulation development, upstream and downstream development.  Represent the analytical development group on analytical method transfer and validation teams at commercial QC lab.  Represent the analytical development group on CMC team.  Present scientific data to both internal audiences within the company and external scientific span colleagues. Follow /span SOPs, policies, and regulations, perform lab experiments, and maintain equipment . /p p /p