Scientist II / Senior Scientist I - In Vivo Antibody Discovery
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POST DATE 7/21/2020
END DATE 8/9/2020
JOB DESCRIPTIONABOUT ABBVIE
AbbVie s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.
TheBiologics Generation Group within Global Biologics is seeking a highlymotivated research scientist to join the in vivo antibody discovery teamat AbbVie Bioresearch Center (ABC). TheABC site, based in Worcester, MA, offers the unique setting where Biologicsdrug discovery, development and manufacturing coexist in one location. Our team interacts with multidisciplinarygroups across AbbVie focused on developing therapies for Immunology, Neurology,Oncology and Virology. We utilizeinnovative immunization approaches, advanced multiplex screening assays andbest-in-class automation platforms to enable successful antibody discoveryagainst complex targets.
We are seeking an accomplished scientist who will makesubstantial contributions to the conception, execution and communication ofantibody discovery strategies against pathogenic viruses. A primaryresponsibility of the successful candidate will be to develop and executeresearch strategies to enable the discovery and development of therapeuticantibodies against pathogenic viruses. Main responsibilities will include thedesign and execution of in vivo lead antibodyidentification/optimization and collaborating to generate stage-gateappropriate in vitro / cellular / in vivo data packages supporting proof-ofconcept. The candidate will leverage expertise to develop and implementresearch to gain a mechanistic understanding of the molecular pharmacology of therapeuticmolecules. The successful candidate will be responsible for driving antibodydiscovery programs within a multidisciplinary research group in an exciting,fast-paced team environment.
PhD or equivalent in immunology or virology fields; BS & 10+ years of experience; MS & 8+ years of experience.
Knowledge of molecular biology, immunology and virology concepts
Experience with aseptic mammalian cell culture
Experience in viral neutralization assays and immunoassays (flow cytometry, ELISA, homogeneous assays and microscopy
Strong attention to quality and details when exercising organizational, documentation and communication skills
Proven flexibility to deal with changing timelines and shifting work priorities
Competency with software programs, including MS Excel, PowerPoint, Word
Experience with handling human blood samples
Experience with microfluidics and single cell analysis and advanced automation platforms
Molecular biology techniques including molecular cloning
Animal handling experience (e.g. restraint, immunizations, tissue harvesting etc.)
KEY ABBVIE COMPETENCIES:
* Builds strong relationships with peers and cross functionally with partners outside of the team to enable higher performance.
* Learns fast, grasps the essence and can change the course quickly where indicated.
* Raises the bar and is never satisfied with the status quo.
* Creates a learning environment, open to suggestions and experimentation for improvement.
* Embraces the ideas of others, nurtures innovation and manages innovation to reality.
SIGNIFICANT WORK ACTIVITIES
Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Yes, 5 % of the Time
JOB LEVEL CODE
EQUAL EMPLOYMENT OPPORTUNITY
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.